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Table 1. Risks and Benefits for Hormone Therapy in the WHI Hormone Trial
Estrogen plus progestin (versus placebo)
Estrogen alone
5
(versus placebo)
Event
Hazard ratio
Extra events/10,000 women/year
Decrease in events/10,000 women/year
Hazard ratio
Extra events/10,000 women/year
Decrease in events/10,000 women/year
Coronary heart disease
6
1.24
+6
0.91
–5
Breast cancer
7
1.24
+8
0.77
–7
Stroke
8
1.31
+7
1.39
+12
Venous thromboembolism
9
2.06
+18
1.33
+7
Colorectal cancer
10
0.63
–6
1.08
+1
Hip fractures
11
0.67
–5
0.61
–6
Total fractures
12
0.76
–47
0.70
–56
Table citations appear at end of article.
