New Emergency Contraception Developments
NEWS IN CONTEXT
One-dose formulation is approved; two-dose formulation goes generic.
CME
Reviewing:
North Wales, PA: Teva Pharmaceuticals, Inc. 2009 Jul 10
Budapest, Hungary: Gedeon Richter, Ltd., for Duramed Pharmaceuticals, Inc. 2009
Silver Spring, MD: Food and Drug Administration 2009 Jun 24
Does Migraine Frequency Affect CVD Risk?
SUMMARY AND COMMENT
Rare (<monthly) and frequent ( weekly) migraines were associated with excess risk for CVD events.
Reviewing:
Kurth T et al., Neurology 2009 Jun 24
Community-Based Interventions Promote Heart-Healthy Behaviors
SUMMARY AND COMMENT
Older women (age range, 51–70) who participated in a program to promote physical activity and healthful diets lost weight and improved their exercise habits.
Reviewing:
Folta SC et al., Am J Public Health 2009 Jul; 99:1271
Just in Time for Summer: Grilled Meats Don't Cause Breast Cancer
SUMMARY AND COMMENT
Consumption of meat cooked at high temperatures was not associated with breast cancer in a large prospective cohort of postmenopausal women.
Reviewing:
Kabat GC et al., Int J Cancer 2009 May 15; 124:2430
A FASTTer Path to Pregnancy for Couples with Unexplained Infertility?
SUMMARY AND COMMENT
Bypassing gonadotropin-stimulated artificial insemination was associated with shorter time to pregnancy and lower risk for multiple births.
Reviewing:
Reindollar RH et al., Fertil Steril 2009 Jun 16
Menopausal HT and Ovarian Cancer: Causal Role Remains Unclear
SUMMARY AND COMMENT
A Danish prospective cohort study showed HT use was associated with modest excess risk.
Reviewing:
Mørch LS et al., JAMA 2009 Jul 15; 302:298
At Puberty, Daughters of Women with PCOS Differ from Daughters of Normal Women
SUMMARY AND COMMENT
PCOS daughters tended to have greater ovarian volume and hyperinsulinemia in glucose tolerance tests.
Reviewing:
Sir-Petermann T et al., J Clin Endocrinol Metab 2009 Jun; 94:1923
Extending the Age Range for HPV Vaccination? Dont Faint
SUMMARY AND COMMENT
Quadrivalent HPV vaccine was effective in HPV-naive women, aged 24–45; FDA strengthens syncope warning.
Reviewing:
Muñoz N et al., Lancet 2009 Jun 6; 373:1949
U.S. Food and Drug Administration (FDA)., 2009 Jun 18
Boning Up on Thiazolidinediones
SUMMARY AND COMMENT
Rosiglitazone was associated with excess fracture risk in women.
Reviewing:
Home PD et al., Lancet 2009 Jun 20; 373:2125
Diagnosis and Management of von Willebrand Disease and Other Bleeding Disorders in Women
PRACTICE WATCH
Bleeding disorders are important causes of heavy menstrual bleeding and postpartum hemorrhage.
Reviewing:
James AH et al., Am J Obstet Gynecol 2009 Jul; 201:e1