Pregnancy and the Flu
SUMMARY AND COMMENT
Pandemic H1N1 and seasonal influenza take their toll on pregnant women; vaccination is a top priority.
Reviewing:
Jamieson DJ et al., Lancet 2009 Aug 8; 374:451
MacDonald NE et al., Obstet Gynecol 2009 Aug; 114:365
Phillippe M., Obstet Gynecol 2009 Aug; 114:206
Atlanta, GA: Centers for Disease Control and Prevention (CDC) 2009 Jul 29
The Other Shoe Drops: New WHI Analysis
SUMMARY AND COMMENT
Unfavorable balance of risks and benefits also applies to women who initiated HT within 5 years after menopause.
Reviewing:
Prentice RL et al., Am J Epidemiol 2009 Jul 1; 170:12
Banks E and Canfell K., Am J Epidemiol 2009 Jul 1; 170:24
Screening Detects Many Breast Cancers, but How Many Are Overdiagnosed?
SUMMARY AND COMMENT
Population-wide mammography screening is associated with higher incidence of breast cancer, but the estimated overdiagnosis rate is more than 50%.
Reviewing:
Jørgensen KJ and Gøtzsche PC., BMJ 2009 Jul 9; 339:b2587
Welch HG., BMJ 2009 Jul 9; 339:b1425
Maternal Smoking Rates During Pregnancy Drop . . . A Little
SUMMARY AND COMMENT
Rates of smoking during and after pregnancy declined somewhat from 2000 through 2005, but smoking prevalence before conception did not change.
Reviewing:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Surveill Summ 2009 May 29; 58:1
Magnesium Sulfate to Prevent Cerebral Palsy in Preterm Infants: Gathering the Evidence
SUMMARY AND COMMENT
Results of a meta-analysis support use of magnesium sulfate in women at risk for preterm delivery before 34 weeks' gestation.
Reviewing:
Conde-Agudelo A and Romero R., Am J Obstet Gynecol 2009 Jun; 200:595
Does Hormonal Contraception Accelerate HIV Progression?
SUMMARY AND COMMENT
Use of either DMPA or OCPs was associated with hastened unfavorable disease outcomes.
Reviewing:
Stringer EM et al., AIDS 2009 Jul 17; 23:1377
Does Circumcision of HIV-Infected Men Prevent HIV Acquisition in Their Female Partners?
SUMMARY AND COMMENT
Risk for HIV transmission was highest among couples who resumed sexual activity before wound healing was complete.
Reviewing:
Wawer MJ et al., Lancet 2009 Jul 18; 374:229
Baeten JM et al., Lancet 2009 Jul 18; 374:182
Some Migraines Might Leave Their Marks
SUMMARY AND COMMENT
Women who reported migraines with aura in midlife were twice as likely to exhibit cerebellar infarcts on MRI, with unknown clinical significance, decades later.
Reviewing:
Scher AI et al., JAMA 2009 Jun 24; 301:2563
Kurth T and Tzourio C., JAMA 2009 Jun 24; 301:2594
Is Monitoring BMD Necessary in Patients Who Take Bisphosphonates?
SUMMARY AND COMMENT
Alendronate treatment increases bone density in most patients, so routine monitoring of BMD is not warranted.
Reviewing:
Bell KJL et al., BMJ 2009 Jun 23; 338:b2266
Early Menopause, Excess Weight Dramatically Raise Endometrial Cancer Risk
SUMMARY AND COMMENT
Overweight and obese women who enter menopause before age 45 have 6-fold and 20-fold excess risk for endometrial cancer, respectively.
Reviewing:
Thomas CC et al., Obstet Gynecol 2009 Jul; 114:22