Vaginal Estrogen Relieves Postmenopausal Vaginal Symptoms
SUMMARY AND COMMENT
Three different regimens of vaginal estrogen were better than placebo at relieving women's most bothersome symptoms, primarily vaginal dryness and dyspareunia.
Reviewing:
Bachmann G et al., Menopause 2009 Jul/Aug; 16:719
Freedman M et al., Menopause 2009 Jul/Aug; 16:735
Quadrivalent HPV Vaccine: Postlicensure Safety Data and Marketing Controversies
SUMMARY AND COMMENT
September 3, 2009
Ann J. Davis, MD
Causal nature of qHPV vaccination in relation to adverse events remains unclear; marketing has been criticized for focusing on cervical cancer prevention.
Reviewing:
Slade BA et al., JAMA 2009 Aug 19; 302:750
Rothman SM and Rothman DJ., JAMA 2009 Aug 19; 302:781
Haug C., JAMA 2009 Aug 19; 302:795
Ovarian Status and Risk for Lung Cancer
SUMMARY AND COMMENT
Further evidence that functional ovaries protect against lung cancer
Reviewing:
Koushik A et al., Int J Cancer 2009 May 11
DMPA and Weight Gain
SUMMARY AND COMMENT
September 3, 2009
Ann J. Davis, MD
Initial excessive weight gain with DMPA use predicted continued excessive gain.
Reviewing:
Le Y-CL et al., Obstet Gynecol 2009 Aug; 114:279
Speaking Bluntly About Needles for Cesarean-Delivery Closure
SUMMARY AND COMMENT
August 27, 2009
Ann J. Davis, MD
Blunt needles led to fewer glove perforations than sharp needles.
Reviewing:
Sullivan S et al., Obstet Gynecol 2009 Aug; 114:211
Does It Matter Whether We Ask About Intimate Partner Violence?
SUMMARY AND COMMENT
Women who were screened about intimate partner violence did not experience lower IPV incidence or better quality of life.
Reviewing:
MacMillan HL et al., JAMA 2009 Aug 5; 302:493
Moracco KE and Cole TB., JAMA 2009 Aug 5; 302:568
Salivary Testosterone Levels Do Not Reflect Serum Levels in Postmenopausal Women
SUMMARY AND COMMENT
Poor correlation does not support routine measurement of salivary testosterone.
Reviewing:
Flyckt RL et al., Menopause 2009 Jul/Aug; 16:680
Strength Training: Safe in Breast Cancer Survivors with Lymphedema
SUMMARY AND COMMENT
Weight lifting did not exacerbate breast-cancer–related lymphedema.
CME
Reviewing:
Schmitz KH et al., N Engl J Med 2009 Aug 13; 361:664
Girlhood Cancer Treatment and Subsequent Breast Cancer Risk
SUMMARY AND COMMENT
Radiation dose-response curves were linear; this relation was attenuated in women who received pelvic radiation sufficient to abolish ovarian function.
CME
Reviewing:
Inskip PD et al., J Clin Oncol 2009 Jul 20
A New Agent for Postmenopausal Osteoporosis?
SUMMARY AND COMMENT
Biannual subcutaneous denosumab injections prevented vertebral, nonvertebral, and hip fractures.
Reviewing:
Cummings SR et al., N Engl J Med 2009 Aug 20; 361:756
Khosla S., N Engl J Med 2009 Aug 20; 361:818
