Women's Health: Archives

SUMMARY AND COMMENT

Reassuring Pregnancy Outcomes in Childhood Cancer Survivors

• November 19, 2009
• Ann J. Davis, MD

Offspring of women with childhood cancer histories were not at excess risk for malformations or infant death; preterm birth and cesarean delivery were somewhat more common among childhood cancer survivors.

• Reviewing:
• Mueller BA et al., Arch Pediatr Adolesc Med 2009 Oct; 163:879

SUMMARY AND COMMENT

Stability of U.K. Down Syndrome Birth Rate: Age-Related Risks Offset by Antenatal Screening

• November 19, 2009
• Wendy S. Biggs, MD

From 1989 through 2008, better antenatal screening for Down syndrome kept the number of affected live births constant despite a shift toward older maternal age at delivery.

• Reviewing:
• Morris JK and Alberman E., BMJ 2009 Oct 26; 339:b3794

SUMMARY AND COMMENT

Breast Tenderness After Starting Menopausal HT: An Ominous Sign?

• November 19, 2009
• Andrew M. Kaunitz, MD

In the WHI trial, HT users with new-onset breast tenderness had higher risk for breast cancer than did HT users without this side effect.

• Reviewing:
• Crandall CJ et al., Arch Intern Med 2009 Oct 12; 169:1684

SUMMARY AND COMMENT

BRCA Testing of Women with Ovarian Cancer: Which Strategy Is Best?

• November 19, 2009
• Andrew M. Kaunitz, MD

Testing women of Ashkenazi Jewish ancestry or with family histories of breast or ovarian cancer was projected to be cost-effective for lowering subsequent cancer rates among first-degree relatives.

• Reviewing:
• Kwon JS et al., J Clin Oncol 2009 Oct 19

SUMMARY AND COMMENT

For Detecting CIN, Cytology Method Might Not Matter

• November 19, 2009
• Wendy S. Biggs, MD

Liquid-based cytology was as sensitive and specific as conventional Pap tests.

• Reviewing:
• Siebers AG et al., JAMA 2009 Oct 28; 302:1757 Schiffman M and Solomon D., JAMA 2009 Oct 28; 302:1809

SUMMARY AND COMMENT

Intravenous Bisphosphonate Therapy for Postmenopausal Women with Low Bone Mass

• November 19, 2009
• Andrew M. Kaunitz, MD

IV zoledronic acid prevented bone loss.

• Reviewing:
• McClung M et al., Obstet Gynecol 2009 Nov; 114:999

CLINICAL PRACTICE GUIDELINE WATCH

Breast Cancer Screening: Who, When, and How?Free

• November 16, 2009
• Andrew M. Kaunitz, MD

New USPSTF guidelines narrow the proposed age range for screening mammography and recommend biennial screening.

• Reviewing:
• U.S. Preventive Services Task Force., Ann Intern Med 2009 Nov 17; 151:716 Mandelblatt JS et al. for the Breast Cancer Working Group of the Cancer Intervention and Surveillance Modeling Network (CISNET)., Ann Intern Med 2009 Nov 17; 151:738 Kerlikowske K., Ann Intern Med 2009 Nov 17; 151:750

PRACTICE WATCH

Contraception for Women Who Receive Anticoagulant Therapy for Venous Thrombosis

• November 12, 2009
• Andrew M. Kaunitz, MD

The levonorgestrel IUD and injectable contraception are safe and effective options with noncontraceptive benefits.

• Reviewing:
• Culwell KR and Curtis KM., Contraception 2009 Oct; 80:337

SUMMARY AND COMMENT

When Biology Meets Personal Choices

• November 12, 2009
• Anna Wald, MD, MPH

Risks for ischemic stroke and myocardial infarction were substantially higher in women with lupus anticoagulant who smoked or used oral contraceptives.

• Reviewing:
• Urbanus RT et al., Lancet Neurol 2009 Nov; 8:998

SUMMARY AND COMMENT

Vaginal Danazol for Abnormal Uterine Bleeding

• November 12, 2009
• Robert W. Rebar, MD

Danazol shortened duration and diminished severity of menstrual bleeding with minimal side effects.

• Reviewing:
• Luisi S et al., Fertil Steril 2009 Oct; 92:1351